2021 Mercedes-Benz GLS450 Problems, Complaints & Recalls

Source: NHTSA · Updated Nov 24, 2025 · 30 owner complaints analyzed

Compared with other GLS450 years
About as many complaints as other years 3rd of 6 for complaints
NHTSA crash rating
Not rated

Owners have filed 30 complaints with NHTSA about the 2021 Mercedes-Benz GLS450. That ranks 3rd out of 6 GLS450 model years for complaints. The most reported problem area is electrical system (14 complaints, 47%), typically at around 11,000 miles. Complaints mention 1 crash, 2 fires, 1 injury. There are 12 safety recalls covering this model year.

Complaints are unverified owner reports and are not adjusted for sales volume.

Compare with another car

Most common 2021 Mercedes-Benz GLS450 problems

Complaints grouped by the part of the car owners reported, with the median mileage when the problem happened.

Electrical System14 · ~11,000 mi
Unknown or Other8
Engine3 · ~11,000 mi
Lane Departure3
Forward Collision Avoidance2 · ~3,000 mi
Seats2
Fuel System, Gasoline1
Power Train1 · ~11,000 mi
Seat Belts1 · ~25,000 mi
Structure1
Problem areaComplaintsShareMedian milesOwners mention mostTypical repair cost
Electrical System1447%11,000——
Unknown or Other827%———
Engine310%11,000——
Lane Departure310%———
Forward Collision Avoidance27%3,000——
Seats27%———
Fuel System, Gasoline13%———
Power Train13%11,000——
Seat Belts13%25,000——
Structure13%———
Tires13%———
Vehicle Speed Control13%3,000——
Visibility/wiper13%———
Wheels13%———

One complaint can list several problem areas, so shares can add up to more than 100%.

Complaints by year received

Peak: 2022, with 10 complaints
2021: 2202122022: 102022102023: 8202382024: 7202472025: 320253

n = 30 complaints · Source: NHTSA

2021 Mercedes-Benz GLS450 recalls (12)

Tap a recall to see the problem, the risk and the fix.

Electrical system:wiringMar 15, 2024 · NHTSA campaign 24V207000 · 116,020 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 GLE 350, 2020-2024 GLE 450, 2020-2023 GLS 580, GLE 580, 2019-2023 GLS 450, 2021-2023 Maybach GLS 600, AMG GLS 63, 2021-2024 AMG GLE 53, AMG GLE 53 Coupe, and AMG GLE 63 S vehicles. A 48-Volt ground connection under the passenger seat may not be secured properly, resulting in the ground connection overheating.

Risk: An overheated ground connection can increase the risk of a fire.

Fix: Dealers will inspect and tighten the 48-Volt ground connection as necessary, free of charge. Owner notification letters were mailed on May 3, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040002.

Power train:automatic transmission:control module:softwareFeb 16, 2024 · NHTSA campaign 24V118000 · 105,071 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2023 GLE 450 and GLS 450 vehicles. The transmission may not fully downshift in certain conditions, causing the engine to stall.

Risk: An engine stall increases the risk of a crash.

Fix: Dealers will update the transmission control unit software, free of charge. Owner notification letters were mailed March 29, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.

Fuel system, gasoline:delivery:fuel pumpJun 26, 2023 · NHTSA campaign 23V445000 · 143,551 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

Risk: A loss of drive power can increase the risk of a crash.

Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

Visibility:defroster/defogger/hvac systemMar 17, 2023 · NHTSA campaign 23V177000 · 61,450 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2021 GLE350, GLE450, GLS450, GLS580, 2021 AMG GLE53, AMG GLE63, Maybach GLS600, AMG GLS63, and 2020 GLE580 vehicles. The air conditioner drain hoses may have been incorrectly installed, causing water to drain into the passenger compartment.

Risk: Water intrusion into the foot wells may cause corrosion and/or short circuits to electrical components, increasing the risk of fire. In addition, the emergency call (eCall) feature may be disabled and the doors may not unlock, increasing the risk of injury. Also, the engine may not start or may enter a limp-home mode, increasing the risk of a crash.

Fix: Dealers will inspect and reinstall the air conditioner drain hoses, as necessary, free of charge. Owner notification letters were mailed April 28, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall numbers 21V-288 and 19V-587. MBUSA's numbers for this recall are 2023030014 and 15.

Seats:mid/rear assemblySep 30, 2022 · NHTSA campaign 22V732000 · 59,574 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 AMG GLS63, 2020-2022 GLS450 and GLS580 vehicles. Due to a manufacturing error, the locks on the third-row seatbacks may fail in the event of a crash.

Risk: A seat with a seatback lock failure may not properly restrain occupants, increasing the risk of injury during a crash.

Fix: Dealers will inspect and replace the third-row seatback, as necessary, free of charge. Owner notification letters were mailed November 18, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100011.

Structure:bodySep 12, 2022 · NHTSA campaign 22V680000 · 161,000 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE350, GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, and 2021 GLE400e, AMG GLS63, AMG GLE63 S, and Maybach GLS600 vehicles. Due to a manufacturing error, the rear door window trim bars may detach.

Risk: Detached trim bars may cause a road hazard and increase the risk of a crash or injury.

Fix: Dealers will inspect and secure the rear window trim bars, as necessary, free of charge. Owner notification letters were mailed November 1, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022090010.

Electrical system:software; communication: auto crash notificationMay 20, 2022 · NHTSA campaign 22V365000 · 242,722 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Electrical system:wiring:interior/under dashApr 8, 2022 · NHTSA campaign 22V231000 · 21,306 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, 2021 AMG GLE63, Maybach GLS600 and AMG GLS63 vehicles. A ground cable bolt for the 48V ground connection under the front passenger seat may not be secured properly, which can cause the electrical cable to overheat.

Risk: An overheated electrical cable can increase the risk of a fire.

Fix: Dealers will inspect and tighten the ground cable bolt, as necessary, free of charge. Owner notification letters were mailed July 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040017.

Visibility:glass, side/rearOct 22, 2021 · NHTSA campaign 21V832000 · 23 vehicles

Problem: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 GLE 350, GLE 580, GLS 450, GLS 580, AMG GLE 53, AMG GLE 63 S, and AMG GLS 63 S vehicles. The rear window may be insufficiently bonded to the tailgate, which could allow the rear glass to detach.

Risk: Detached rear glass can become a road hazard, increasing the risk of a crash.

Fix: Dealers will replace the rear window, free of charge. Owner notification letters were mailed December 8, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Back over prevention: sensing system: camera; electrical system:softwareMay 14, 2021 · NHTSA campaign 21V354000 · 343,191 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.

Fix: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Communication: auto crash notification; electrical system:softwareFeb 5, 2021 · NHTSA campaign 21V058000 · 1,292,258 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.

Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.

Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Electrical system: instrument cluster/panelFeb 14, 2020 · NHTSA campaign 20V089000 · 2,101 vehicles

Problem: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2020 CLA250, CLA250 4MATIC and CLA35 AMG 4MATIC, 2020-2021 GLE350, GLE350 4MATIC, GLE450 4MATIC, GLS450 4MATIC and GLS580 4MATIC and 2021 GLE53 AMG Coupe, GLE63S AMG 4MATIC, GLS63 AMG 4MATIC and Maybach GLS600 4MATIC vehicles. The instrument cluster software may deactivate the illumination of certain interior switches (switch bar, overhead control unit, steering wheel) if the hazard lights are turned on and the ignition switch is in the 'off' position. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 101, "Control and Displays."

Risk: If the interior switches are not illuminated, they may be more difficult to find and operate, increasing the risk of a crash.

Fix: MBUSA will notify owners, and dealers will update the instrument cluster software, free of charge. The recall began March 31, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020030019.

To see whether a specific car still has an open recall, enter its VIN on NHTSA's official recall lookup. You can also decode a VIN here.

Recent owner reports

Short excerpts of the latest complaints filed with NHTSA, with personal details removed. Full reports can be searched on NHTSA.gov.

Both rear wheels on this vehicle have developed cracks which leads to tire pressure loss. Apparently, this is a common issue with Mercedes' heavier vehicles like the GLS and S series sedans. To be clear, I did not hit anything. I did not do any unusual driving. Both rear tires are fine. While you…

Wheels · received Nov 24, 2025 · NHTSA complaint 11701188

On [XXX], I was heading home from work traveling [XXX] on [XXX] through Atlanta's usual heavy traffic. I smelled smoke inside my car and saw fire flames coming from under my passenger seat. My initial reaction was to try to put the fire out with my hat without burning myself. Also, I had to try to…

Seats · received May 16, 2025 · NHTSA complaint 11661377

System malfunctioned detail: 48v battery malfunction, 12v battery malfunction. Safety concern: I was driving on [XXX] , the battery malfunction warning suddenly pop up, and I couldn't accelerate my car beyond 30 MPH, my whole family were on the car during that time. it's life threatening issue…

Electrical System · received Jan 5, 2025 · NHTSA complaint 11634240

Vehicle has just over 31k miles. ON multiple occasions, the vehicle randomly shuts off and displays a 48 volt battery error on the screen followed by a check engine light. This has happened in the middle of a busy intersection and at 75mph on the interstate. Each time it does this, I have taken it…

Electrical System · received Nov 13, 2024 · NHTSA complaint 11624928

I was driving only 30mph through my suburban neighborhood bringing my kids to school in the morning when a loud shotgun sound hit my car causing me to be distracted and distraught. My entire sunroof had exploded on me for no reason. Mercedes is currently undergoing a class action lawsuit for this…

Unknown or Other · received Sep 25, 2024 · NHTSA complaint 11616529

Other Mercedes-Benz GLS450 years

← 2020 GLS450

YearComplaintsRecalls
20213012
2020 GLS4503622
2019 GLS450243
2018 GLS450143
2017 GLS450358
2016 GLS45001

See all Mercedes-Benz GLS450 problems by year, every Mercedes-Benz model, or the Mercedes-Benz VIN decoder.

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Frequently asked questions

What are the most common problems with the 2021 Mercedes-Benz GLS450?

Owners most often report electrical system, unknown or other, engine problems. The top one, electrical system, accounts for 14 complaints.

Was there a recall on the 2021 Mercedes-Benz GLS450?

Yes, 12 safety recalls. Enter your VIN at NHTSA.gov to check whether the repairs were done on your car.

Was the 2021 Mercedes-Benz GLS450 a good year?

Complaint data can't fully answer that, because counts aren't adjusted for sales. Compared with other GLS450 model years, the 2021 has about as many complaints as a typical year. Always get a pre-purchase inspection and check the VIN for open recalls.