2010 Mercedes-Benz E350 Problems, Complaints & Recalls

Source: NHTSA · Updated Sep 30, 2026 · 184 owner complaints analyzed

Compared with other E350 years
Far more complaints than other years 6th of 22 for complaints
NHTSA crash rating
Not rated

Owners have filed 184 complaints with NHTSA about the 2010 Mercedes-Benz E350. That ranks 6th out of 22 E350 model years for complaints. The most reported problem area is air bags (68 complaints, 37%), typically at around 54,978 miles. Complaints mention 9 crashes, 6 injuries. There are 4 safety recalls covering this model year. NHTSA has opened 2 defect investigations involving it.

Complaints are unverified owner reports and are not adjusted for sales volume.

Compare with another car

Most common 2010 Mercedes-Benz E350 problems

Complaints grouped by the part of the car owners reported, with the median mileage when the problem happened.

Air Bags68 · ~54,978 mi
Unknown or Other19 · ~65,000 mi
Fuel/propulsion System18 · ~80,000 mi
Electrical System17 · ~73,000 mi
Suspension17 · ~88,030 mi
Engine15 · ~59,948 mi
Power Train14 · ~94,000 mi
Service Brakes11 · ~91,500 mi
Structure11 · ~36,200 mi
Steering8 · ~120,850 mi
Problem areaComplaintsShareMedian milesOwners mention mostTypical repair cost
Air Bags problems6837%54,978“takata air bags” (12%)—
Unknown or Other1910%65,000——
Fuel/propulsion System1810%80,000——
Electrical System179%73,000——
Suspension179%88,030——
Engine158%59,948——
Power Train148%94,000——
Service Brakes116%91,500——
Structure116%36,200——
Steering84%120,850——
Exterior Lighting53%7,400——
Seats42%48,000——
Vehicle Speed Control42%27,000——
Electronic Stability Control (esc)32%39,500——
Service Brakes, Hydraulic32%85,788——
Tires32%7,574——
Wheels32%35,849——
Equipment21%10,000——
Fuel System, Gasoline21%72,075——
Lane Departure21%———
Engine and Engine Cooling11%2,694——

One complaint can list several problem areas, so shares can add up to more than 100%.

Complaints by year received

Peak: 2017, with 46 complaints
2009: 3200932010: 992011: 2201122012: 112013: 1201312014: 772015: 5201552016: 11112017: 462017462018: 27272019: 132019132020: 882021: 6202162022: 12122023: 142023142024: 332025: 122025122026: 44

n = 184 complaints · Source: NHTSA

2010 Mercedes-Benz E350 recalls (4)

Tap a recall to see the problem, the risk and the fix.

Exterior lighting:lighting control module:software; engine and engine cooling:engine:engine control module (ecu/ecm):software; electronic stability control (esc):control module:softwareMar 18, 2022 · NHTSA campaign 22V168000 · 22 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.

Risk: Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.

Fix: Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.

Air bags:frontal:passenger side:inflator moduleJan 10, 2018 · NHTSA campaign 18V043000 · 132,167 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands or "Zone A." Additionally, MBUSA is recalling certain 2010 C300, C300 4Matic, C63 AMG, E350 Coupe, E550 Coupe, GLK350, and GLK350 4Matic vehicles ever registered in the states of Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia or "Zone B." MBUSA is also recalling certain 2009 C300, C300 4Matic, C63 AMG, and C350 vehicles ever registered in the states of AK, CO, CT, ID, IA, ME, MA, MI, MN, MO, NH, NY, ND, OR, RI, SD, UT, VT, WA, WI and WY or "Zone C." In the event of a crash necessitating deployment of the passenger frontal air bag, these passenger air bag inflator may explode due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Risk: An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.

Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Air bags:frontal:passenger side:inflator moduleMay 26, 2016 · NHTSA campaign 16V363000 · 258,163 vehicles

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands, or "Zone A." Additionally, unless included in "Zone A" above, MBUSA is recalling certain model year 2008 C300 Sedan, C350 Sedan, C63 AMG Sedan and C300 4-Matic Sedan vehicles originally sold, or ever registered, in Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia, or "Zone B." Vehicles not originally sold or ever registered in either Zones A or B are not subject to this safety recall. These vehicles are equipped with certain air bag inflators assembled as part of the passenger frontal air bag modules, and used as original equipment or replacement equipment. In the event of a crash necessitating deployment of the front air bags, these inflators may rupture due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Risk: An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.

Fix: MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Air bags:frontal:driver side:inflator moduleFeb 11, 2016 · NHTSA campaign 16V081000 · 711,159 vehicles

Problem: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-2014 SLS AMG Coupe, 2012 SLS AMG Cabriolet, 2013-2014 SLS AMG GT and SLS AMG GT Cabriolet, 2005 C230 Kompressor and C320, 2006-2007 C230, 2006-2011 C350, 2008-2011 C300 and C300 4Matic, 2010-2012 GLK350 and GLK350 4Matic and 2007-2008 Chrysler Crossfire vehicles. Upon deployment of the driver's frontal air bag, excessive internal pressure may cause the inflator to rupture.

Risk: In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.

Fix: MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.

To see whether a specific car still has an open recall, enter its VIN on NHTSA's official recall lookup. You can also decode a VIN here.

NHTSA defect investigations

  • Desiccated Air Bag Inflator Rupture (EA21002) — opened Sep 17, 2021, still open.
  • Rear brake line failure (DP20004) — opened Apr 24, 2020, closed Oct 9, 2020.

Recent owner reports

Short excerpts of the latest complaints filed with NHTSA, with personal details removed. Full reports can be searched on NHTSA.gov.

While I was driving the Issues with the steering column module (SCM) sudden loss of critical driver controls, erratic electrical behavior. It failed to communicate properly with the power steering system, alongside dashboard warnings for the Electronic Stability Program (ESP) and Antilock Braking…

Steering · received Sep 30, 2026 · NHTSA complaint 11768160

I am writing to formally submit a complaint regarding my 2010 E350 (VIN # [XXX] ). I have taken great pride in owning and maintaining this vehicle, and I want to share my concerns based on my recent experience. I have consistently kept this car well-maintained, following all recommended service…

Service Brakes · received Apr 10, 2026 · NHTSA complaint 11730465

All of sudden blind spot inoperable , turning signal to Rt. , signal goes LT. OR TURNING SIGNAL TO LT. , SIGNAL GOES To RT.

Exterior Lighting · received Feb 17, 2026 · NHTSA complaint 11718667

Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot. Also…

Service Brakes · received Jan 19, 2026 · NHTSA complaint 11711970

It seems like brake lines corroded and need to be replaced. Same issue in this car with subframe and that was taken care of by the extended warranty but brake lines were not part of extended warranty? That should be investigated further. Rear subframe rust out and brake line corrosion are obviously…

Service Brakes · received Nov 24, 2025 · NHTSA complaint 11701296

Other Mercedes-Benz E350 years

← 2009 E350 · 2011 E350 →

See all Mercedes-Benz E350 problems by year, every Mercedes-Benz model, or the Mercedes-Benz VIN decoder.

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Frequently asked questions

What are the most common problems with the 2010 Mercedes-Benz E350?

Owners most often report air bags, unknown or other, fuel/propulsion system problems. The top one, air bags, accounts for 68 complaints.

Was there a recall on the 2010 Mercedes-Benz E350?

Yes, 4 safety recalls. Enter your VIN at NHTSA.gov to check whether the repairs were done on your car.

Was the 2010 Mercedes-Benz E350 a good year?

Complaint data can't fully answer that, because counts aren't adjusted for sales. Compared with other E350 model years, the 2010 has far more complaints than most years. Always get a pre-purchase inspection and check the VIN for open recalls.