2006 Mercedes-Benz E350 Fuel/propulsion System Problems

Source: NHTSA · Updated Sep 23, 2026 · 144 complaints analyzed

Owners have filed 144 complaints with NHTSA about fuel/propulsion system problems on the 2006 Mercedes-Benz E350, 36% of all complaints for this model year. Half of the reports with a mileage happened before 96,750 miles. The words owners use most often: “fuel tank” (28% of reports).

What owners describe

Phrases that appear unusually often in these complaints compared with complaints about other cars.

  • Fuel tank: mentioned in 41 of 144 complaints (28%)
  • Gas smell: mentioned in 21 of 144 complaints (15%)
  • Strong odor: mentioned in 17 of 144 complaints (12%)
  • Inside outside: mentioned in 15 of 144 complaints (10%)

How much does it cost to fix?

Owners who wrote down what they paid or were quoted put the typical fuel/propulsion system repair on the 2006 Mercedes-Benz E350 at $4,000, and half of them between $3,350 and $4,400.

Based on 13 NHTSA complaints about this problem alone that state a repair bill or quote (2012–2023), converted to 2026 dollars with the U.S. consumer price index. These are owners' own figures, not a quote: they include dealer quotes, and owners who file complaints often faced larger repairs, so they can run higher than typical shop prices. Prices vary by shop, region and warranty coverage. How we calculate this.

At what mileage do fuel/propulsion system problems happen?

Based on 120 complaints that reported the odometer reading.

Under 10k miles0 · 0%
10k–25k miles2 · 2%
25k–50k miles14 · 12%
50k–75k miles29 · 24%
75k–100k miles19 · 16%
100k–150k miles37 · 31%
150k+ miles19 · 16%

How serious are the reports?

Of 144 complaints, 1 mention a crash, 5 a fire, 2 an injury.

Mercedes-Benz E350 fuel/propulsion system complaints by model year

Peak: 2007, with 177 complaints
2003: 2200322004: 772005: 2200522006: 1441442007: 17720071772008: 65652009: 272009272010: 18182011: 282011282012: 27272013: 7201372014: 24242015: 2201522016: 222017: 2201722020: 112021: 220212

n = 537 complaints · Source: NHTSA

Model yearFuel/propulsion System complaintsShare of that yearMedian miles
2021 E350215%—
2020 E350113%—
2017 E350229%27,500
2016 E35024%—
2015 E35026%—
2014 E350249%11,000
2013 E35074%36,295
2012 E3502712%74,500
2011 E3502813%59,400
2010 E3501810%80,000
2009 E3502742%98,000
2008 E3506538%92,151
2007 E35017751%80,000
2006 E35014436%96,750
2005 E350213%51,017
2004 E350770%135,000
2003 E350229%188,000

When owners reported it

Peak: 2014, with 35 complaints
2012: 162012162013: 302013302014: 352014352015: 222015222016: 9201692017: 122017122018: 4201842019: 3201932020: 4202042021: 4202142022: 4202242023: 120231

n = 144 complaints · Source: NHTSA

Related recalls (0)

No safety recall lists fuel/propulsion system for the 2006 Mercedes-Benz E350. A pattern of complaints does not always lead to a recall.

What owners report

Short excerpts of recent complaints, with personal details removed. Full reports are on NHTSA.gov.

PZEV fuel tank leaks at top but is not repairable. Replacement requires complete tank replacment which is not economically feasilble. This forces owners to continue to operate vehicle with fuel leakage since repair of the tank is not possible. In older models a simple gasket change would resolve…

Received Mar 19, 2023 · NHTSA complaint 11512596

I recently started smelling gas in my car after refueling. I was told by my mechanic that Mercedes was replacing fuel pumps and fuel tanks free of charge . Mercedes Benz customer care has advised this isn't so. This is an expensive repair and I am hoping Mercedes Benz can cover the cost of this…

Received Dec 14, 2022 · NHTSA complaint 11497476

In June 2017, I received a letter from Mercedes-Benz of America informing me that the warranty of the fuel system in my vehicle is extended to 15 years. In that same year, I had my whole fuel tank replaced by an authorized Mercedes Benz dealer in San Jose, California due to strong smell of fuel by…

Received Nov 11, 2022 · NHTSA complaint 11493193

Frequently asked questions

Do all 2006 Mercedes-Benz E350s have fuel/propulsion system problems?

No. NHTSA has 144 owner complaints about fuel/propulsion system for the 2006 Mercedes-Benz E350 (36% of the 399 complaints for this model year). Complaint data shows that the problem is reported, not how many of all cars sold are affected.

Was there a recall on the 2006 Mercedes-Benz E350 fuel/propulsion system?

No recall currently lists fuel/propulsion system for this vehicle.

At what mileage do fuel/propulsion system problems start?

The median reported mileage is 96,750 miles: half of the reports with a mileage came before that.

How much does it cost to fix fuel/propulsion system problems on the 2006 Mercedes-Benz E350?

Owners report a typical cost of $4,000 (half paid between $3,350 and $4,400), from 13 complaints that state a repair bill or quote, in 2026 dollars.

What do owners say about fuel/propulsion system problems on the 2006 Mercedes-Benz E350?

The most frequent phrase is “fuel tank”, in 41 of 144 complaints, followed by “gas smell” (21).

Other 2006 Mercedes-Benz E350 problems

See all 2006 Mercedes-Benz E350 problems or fuel/propulsion system problems across all E350 years.