2006 Mercedes-Benz E350 Fuel System, Gasoline Problems

Source: NHTSA · Updated Sep 23, 2026 · 78 complaints analyzed

Owners have filed 78 complaints with NHTSA about fuel system, gasoline problems on the 2006 Mercedes-Benz E350, 20% of all complaints for this model year. Half of the reports with a mileage happened before 84,006 miles. The words owners use most often: “fuel tank” (38% of reports).

What owners describe

Phrases that appear unusually often in these complaints compared with complaints about other cars.

  • Fuel tank: mentioned in 30 of 78 complaints (38%)
  • Strong gasoline: mentioned in 18 of 78 complaints (23%)
  • Sending unit: mentioned in 12 of 78 complaints (15%)
  • Gas smell: mentioned in 8 of 78 complaints (10%)

How much does it cost to fix?

Owners who wrote down what they paid or were quoted put the typical fuel system, gasoline repair on the 2006 Mercedes-Benz E350 at $2,850, and half of them between $2,100 and $4,200.

Based on 7 NHTSA complaints about this problem alone that state a repair bill or quote (2013–2014), converted to 2026 dollars with the U.S. consumer price index. These are owners' own figures, not a quote: they include dealer quotes, and owners who file complaints often faced larger repairs, so they can run higher than typical shop prices. Prices vary by shop, region and warranty coverage. How we calculate this.

At what mileage do fuel system, gasoline problems happen?

Based on 72 complaints that reported the odometer reading.

Under 10k miles1 · 1%
10k–25k miles1 · 1%
25k–50k miles10 · 14%
50k–75k miles15 · 21%
75k–100k miles24 · 33%
100k–150k miles18 · 25%
150k+ miles3 · 4%

How serious are the reports?

Of 78 complaints, 1 mention a crash, 1 a fire.

Mercedes-Benz E350 fuel system, gasoline complaints by model year

Peak: 2007, with 79 complaints
2004: 2200422005: 332006: 782006782007: 79792008: 222008222009: 772010: 2201022011: 442012: 8201282013: 442014: 132014132016: 222020: 1202012021: 112022: 120221

n = 227 complaints · Source: NHTSA

Model yearFuel System, Gasoline complaintsShare of that yearMedian miles
2022 E350111%14,403
2021 E35018%53,200
2020 E350113%37,000
2016 E35024%24,020
2014 E350135%88,000
2013 E35042%100,000
2012 E35084%134,180
2011 E35042%112,072
2010 E35021%72,075
2009 E350711%63,250
2008 E3502213%73,758
2007 E3507923%73,551
2006 E3507820%84,006
2005 E350320%82,958
2004 E350220%140,000

When owners reported it

Peak: 2014, with 31 complaints
2010: 2201022011: 4201142012: 7201272013: 302013302014: 312014312015: 2201522018: 1201812021: 120211

n = 78 complaints · Source: NHTSA

Related recalls (0)

No safety recall lists fuel system, gasoline for the 2006 Mercedes-Benz E350. A pattern of complaints does not always lead to a recall.

What owners report

Short excerpts of recent complaints, with personal details removed. Full reports are on NHTSA.gov.

The contact owns a 2006 Mercedes-Benz E350. The contact stated while the vehicle was stationary, she started to smell an abnormal fuel odor from the rear driver’s side seat. The contact stated there was no warning light illuminated. The contact took the vehicle to the local dealer, where it was…

Received Jun 16, 2021 · NHTSA complaint 11421151

The car would not start fuel pump faulty and is part of gas tank bad design cost me close to $3800, some paid by mbz. Mbz replaced 2009 gas tanks for free under warranty but would not do mine. This is a bad design they should have told me about it so i would not buy the car. It is stupid to have to…

Received May 31, 2018 · NHTSA complaint 11099075

Nhtsa action number: pe12001. *tr

Received Apr 22, 2015 · NHTSA complaint 10712303

Frequently asked questions

Do all 2006 Mercedes-Benz E350s have fuel system, gasoline problems?

No. NHTSA has 78 owner complaints about fuel system, gasoline for the 2006 Mercedes-Benz E350 (20% of the 399 complaints for this model year). Complaint data shows that the problem is reported, not how many of all cars sold are affected.

Was there a recall on the 2006 Mercedes-Benz E350 fuel system, gasoline?

No recall currently lists fuel system, gasoline for this vehicle.

At what mileage do fuel system, gasoline problems start?

The median reported mileage is 84,006 miles: half of the reports with a mileage came before that.

How much does it cost to fix fuel system, gasoline problems on the 2006 Mercedes-Benz E350?

Owners report a typical cost of $2,850 (half paid between $2,100 and $4,200), from 7 complaints that state a repair bill or quote, in 2026 dollars.

What do owners say about fuel system, gasoline problems on the 2006 Mercedes-Benz E350?

The most frequent phrase is “fuel tank”, in 30 of 78 complaints, followed by “strong gasoline” (18).

Other 2006 Mercedes-Benz E350 problems

See all 2006 Mercedes-Benz E350 problems or fuel system, gasoline problems across all E350 years.