Mercedes-Benz E350 Electrical System Problems
Owners have filed 179 complaints with NHTSA about electrical system problems on the Mercedes-Benz E350 across 22 model years. The 2014 model year has the most (38). The words owners use most often: “wiring harness” (6% of reports).
- 179electrical system complaints
- —median miles at failure
- 6mention a crash
- 4mention an injury
- 9related recalls
- 33%of reports with a speed happened at 50+ mph
What owners describe
Phrases that appear unusually often in these complaints compared with complaints about other cars.
- Wiring harness: mentioned in 10 of 179 complaints (6%)
At what mileage do electrical system problems happen?
Based on 113 complaints that reported the odometer reading.
How serious are the reports?
Of 179 complaints, 6 mention a crash, 22 a fire, 4 an injury.
Mercedes-Benz E350 electrical system complaints by model year
| Model year | Electrical System complaints | Share of that year | Median miles |
|---|---|---|---|
| 2026 E350 | 1 | 100% | — |
| 2025 E350 | 1 | 50% | — |
| 2024 E350 | 2 | 40% | 9,600 |
| 2023 E350 | 1 | 17% | — |
| 2022 E350 | 1 | 11% | — |
| 2021 E350 | 4 | 31% | — |
| 2020 E350 | 2 | 25% | 400 |
| 2017 E350 | 1 | 14% | — |
| 2016 E350 | 9 | 18% | 41,166 |
| 2015 E350 | 5 | 16% | 25,000 |
| 2014 E350 | 38 | 14% | 49,584 |
| 2013 E350 | 12 | 7% | 39,536 |
| 2012 E350 | 19 | 9% | 70,000 |
| 2011 E350 | 4 | 2% | 65,500 |
| 2010 E350 | 17 | 9% | 73,000 |
| 2009 E350 | 3 | 5% | 63,000 |
| 2008 E350 | 18 | 10% | 116,000 |
| 2007 E350 | 17 | 5% | 88,600 |
| 2006 E350 | 19 | 5% | 66,750 |
| 2005 E350 | 2 | 13% | 164,000 |
| 2004 E350 | 1 | 10% | — |
| 2003 E350 | 2 | 29% | 150,103 |
When owners reported it
Related recalls (9)
Electrical system: instrument cluster/panel
Model years: 2025, 2026
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.
Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.
Fix: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.
Electrical system:wiring
Model years: 2024
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024 E 350 4MATIC, E 450 4MATIC All-Terrain, and E 450 4MATIC vehicles. The 12-Volt and 48-Volt ground connections for the electrical wiring harness may not be secured properly, resulting in the ground connections overheating.
Risk: Overheated ground connections can increase the risk of a fire.
Fix: Dealers will inspect and repair the 12-Volt and 48-Volt ground connections as necessary, free of charge. Owner notification letters were mailed May 7, 2025. Owners may contact MBUSA customer service at 1-800-367-6372.
Electrical system:wiring
Model years: 2024
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024 E350 4Matic, E450 4Matic All-Terrain, and E450 4Matic vehicles. The transmission wiring harness may be routed too close to the driveshaft, which can result in wiring harness damage and cause a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
Fix: Dealers will check the transmission wiring harness routing and correct it, if necessary, free of charge. Owner notification letters were mailed May 17, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040007.
Electrical system:wiring:fuses and circuit breakers
Model years: 2024
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 C300, AMG C43, S580e, S580, Maybach S580, Maybach S680, AMG SL43, AMGSL63, GLC300, EQE350, EQE500, EQS450, EQS580, AMG EQS, 2023 S500, AMG SL55, AMG EQE, 2024 E350, E450, AMG C63e S, CLE300 Coupe, CLE450 Coupe, and GLC300 Coupe vehicles. The 80-Amp fuses may have been manufactured incorrectly, which can cause the fuses to fail.
Risk: An 80-Amp fuse that fails can result in a sudden loss of drive power or a loss of critical safety functions such as the restraint systems or instrument cluster, increasing the risk of a crash or injury. Additionally, there could be an increased risk of a fire.
Fix: Dealers will replace the main fuse boxes, free of charge. Owner notification letters were mailed April 5, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024030008.
Electrical system:adas:blindspot:sensors
Model years: 2023
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023 E450, E350, AMG E63 S, AMG E53, CLS450, AMG GT53, and AMG GT43 vehicles. Due to a software error, the exit warning system audio and visual warnings may fail to alert occupants about approaching vehicles.
Risk: Failure to alert occupants of an approaching vehicle can increase the risk of a crash or injury.
Fix: Dealers will update the exit warning system software, free of charge. Owner notification letters were mailed September 8, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023080005.
Electrical system:software; communication: auto crash notification
Model years: 2020, 2021
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.
Back over prevention: sensing system: camera; electrical system:software
Model years: 2021
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."
Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
Fix: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.
Communication: auto crash notification; electrical system:software
Model years: 2020, 2021
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Electrical system:software; air bags:frontal:sensor/control module-inactive
Model years: 2012, 2013, 2014, 2015, 2016
Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 AMG GT-S, GLC300, CLA250 and GLE300d 4Matic vehicles, 2013 C250, E350 BlueTec and G63 AMG vehicles, 2008-2014 C300 vehicles, 2013-2014 C300 4Matic and ML350 4Matic vehicles, 2009 C350 vehicles, 2014 CLS550, E350 4Matic, E350 Coupe 4Matic, E350 Wagon 4Matic, GLK350 and SL550 vehicles, 2012 CLS550 4Matic vehicles, 2012-2016 E350 vehicles, 2016-2017 GL450 4Matic vehicles, 2012-2014 ML350 4Matic BlueTec vehicles, 2015 S550, S550 4Matic and C300 4Matic Sedan vehicles, 2015-2016 C300 Sedan vehicles, and 2017 SL63 AMG vehicles. Various control units on these vehicles may have been updated with incorrect software, potentially affecting the correct deployment of the air bags in the event of a crash.
Risk: If the air bags do not deploy as intended in the event of a crash, there would be an increased risk of injury in the event of a crash.
Fix: MBUSA will notify owners, and dealers will update software in the affected control units, free of charge. The recall began April 21, 2017. Owners may contact MBUSA customer service at 1-800-367-6372.
What owners report
Short excerpts of recent complaints, with personal details removed. Full reports are on NHTSA.gov.
The contact owns a 2006 Mercedes-Benz E-350. The contact stated that the sensotronic brake control warning was illuminated. The contact researched and found information about warranty coverage for 2006-2010 models with a 25-year warranty. The vehicle was taken to the dealer, who diagnosed that the…
The vehicle was parked when the steering wheel locked , and the headrest. The electrical for my headlight driver side low beam gave me a warning lamp message.
An Intoxalock ignition interlock device was installed in my 2023 Mercedes-Benz E-Class on May 7, 2026. Following installation, the vehicle experienced repeated electrical/no-start problems and incidents in which it became immobilized and could not be moved, requiring towing. On one occasion the…
While driving my 2026 Mercedes-Benz E350 (rear-wheel drive) at approximately 40 mph, I began slowing for a traffic light. As I approached the intersection, the vehicle suddenly experienced what appeared to be a catastrophic electronic failure. Without warning, the vehicle became almost completely…
The digital instrument cluster and center infotainment display screen went completely black and blank while the vehicle was in motion. This immediate failure blinded the driver to critical safety telemetry, including the current vehicle speed, gear positioning, and active safety warning telltales…
Frequently asked questions
Do all Mercedes-Benz E350s have electrical system problems?
No. NHTSA has 179 owner complaints about electrical system for the Mercedes-Benz E350. Complaint data shows that the problem is reported, not how many of all cars sold are affected.
Was there a recall on the Mercedes-Benz E350 electrical system?
Yes: 9 safety recalls list electrical system. Check your VIN on NHTSA.gov to see whether the fix was done on your car.
What do owners say about electrical system problems on the Mercedes-Benz E350?
The most frequent phrase is “wiring harness”, in 10 of 179 complaints.
Other Mercedes-Benz E350 problems
- Fuel/propulsion System problems (537)
- Air Bags problems (396)
- Fuel System, Gasoline problems (227)
- Engine problems (196)
- Service Brakes problems (186)
- Power Train problems (130)
- Suspension problems (117)
- Structure problems (106)
See all Mercedes-Benz E350 problems.