Mercedes-Benz E350 Electrical System Problems

Source: NHTSA · Updated Oct 13, 2026 · 179 complaints analyzed

Owners have filed 179 complaints with NHTSA about electrical system problems on the Mercedes-Benz E350 across 22 model years. The 2014 model year has the most (38). The words owners use most often: “wiring harness” (6% of reports).

What owners describe

Phrases that appear unusually often in these complaints compared with complaints about other cars.

  • Wiring harness: mentioned in 10 of 179 complaints (6%)

At what mileage do electrical system problems happen?

Based on 113 complaints that reported the odometer reading.

Under 10k miles17 · 15%
10k–25k miles2 · 2%
25k–50k miles27 · 24%
50k–75k miles23 · 20%
75k–100k miles17 · 15%
100k–150k miles18 · 16%
150k+ miles9 · 8%

How serious are the reports?

Of 179 complaints, 6 mention a crash, 22 a fire, 4 an injury.

Mercedes-Benz E350 electrical system complaints by model year

Peak: 2014, with 38 complaints
2003: 220032004: 12005: 220052006: 192007: 1720072008: 182009: 320092010: 172011: 420112012: 192013: 1220132014: 38382015: 520152016: 92017: 120172020: 22021: 420212022: 12023: 120232024: 22025: 120252026: 1

n = 179 complaints · Source: NHTSA

Model yearElectrical System complaintsShare of that yearMedian miles
2026 E3501100%—
2025 E350150%—
2024 E350240%9,600
2023 E350117%—
2022 E350111%—
2021 E350431%—
2020 E350225%400
2017 E350114%—
2016 E350918%41,166
2015 E350516%25,000
2014 E3503814%49,584
2013 E350127%39,536
2012 E350199%70,000
2011 E35042%65,500
2010 E350179%73,000
2009 E35035%63,000
2008 E3501810%116,000
2007 E350175%88,600
2006 E350195%66,750
2005 E350213%164,000
2004 E350110%—
2003 E350229%150,103

When owners reported it

Peak: 2020, with 22 complaints
2006: 1200612007: 112008: 1200812010: 442011: 5201152012: 772013: 5201352014: 772015: 142015142016: 882017: 6201762018: 15152019: 122019122020: 22222021: 172021172022: 882023: 122023122024: 13132025: 112025112026: 1010

n = 179 complaints · Source: NHTSA

Related recalls (9)

Electrical system: instrument cluster/panelMay 1, 2026 · NHTSA campaign 26V281000 · 144,049 vehicles

Model years: 2025, 2026

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.

Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.

Fix: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.

Electrical system:wiringApr 11, 2025 · NHTSA campaign 25V240000 · 14 vehicles

Model years: 2024

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024 E 350 4MATIC, E 450 4MATIC All-Terrain, and E 450 4MATIC vehicles. The 12-Volt and 48-Volt ground connections for the electrical wiring harness may not be secured properly, resulting in the ground connections overheating.

Risk: Overheated ground connections can increase the risk of a fire.

Fix: Dealers will inspect and repair the 12-Volt and 48-Volt ground connections as necessary, free of charge. Owner notification letters were mailed May 7, 2025. Owners may contact MBUSA customer service at 1-800-367-6372.

Electrical system:wiringMar 22, 2024 · NHTSA campaign 24V224000 · 396 vehicles

Model years: 2024

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024 E350 4Matic, E450 4Matic All-Terrain, and E450 4Matic vehicles. The transmission wiring harness may be routed too close to the driveshaft, which can result in wiring harness damage and cause a loss of drive power.

Risk: A loss of drive power can increase the risk of a crash.

Fix: Dealers will check the transmission wiring harness routing and correct it, if necessary, free of charge. Owner notification letters were mailed May 17, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040007.

Electrical system:wiring:fuses and circuit breakersFeb 16, 2024 · NHTSA campaign 24V115000 · 31,848 vehicles

Model years: 2024

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 C300, AMG C43, S580e, S580, Maybach S580, Maybach S680, AMG SL43, AMGSL63, GLC300, EQE350, EQE500, EQS450, EQS580, AMG EQS, 2023 S500, AMG SL55, AMG EQE, 2024 E350, E450, AMG C63e S, CLE300 Coupe, CLE450 Coupe, and GLC300 Coupe vehicles. The 80-Amp fuses may have been manufactured incorrectly, which can cause the fuses to fail.

Risk: An 80-Amp fuse that fails can result in a sudden loss of drive power or a loss of critical safety functions such as the restraint systems or instrument cluster, increasing the risk of a crash or injury. Additionally, there could be an increased risk of a fire.

Fix: Dealers will replace the main fuse boxes, free of charge. Owner notification letters were mailed April 5, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024030008.

Electrical system:adas:blindspot:sensorsAug 11, 2023 · NHTSA campaign 23V574000 · 880 vehicles

Model years: 2023

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023 E450, E350, AMG E63 S, AMG E53, CLS450, AMG GT53, and AMG GT43 vehicles. Due to a software error, the exit warning system audio and visual warnings may fail to alert occupants about approaching vehicles.

Risk: Failure to alert occupants of an approaching vehicle can increase the risk of a crash or injury.

Fix: Dealers will update the exit warning system software, free of charge. Owner notification letters were mailed September 8, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023080005.

Electrical system:software; communication: auto crash notificationMay 20, 2022 · NHTSA campaign 22V365000 · 242,722 vehicles

Model years: 2020, 2021

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Back over prevention: sensing system: camera; electrical system:softwareMay 14, 2021 · NHTSA campaign 21V354000 · 343,191 vehicles

Model years: 2021

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.

Fix: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Communication: auto crash notification; electrical system:softwareFeb 5, 2021 · NHTSA campaign 21V058000 · 1,292,258 vehicles

Model years: 2020, 2021

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.

Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.

Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Electrical system:software; air bags:frontal:sensor/control module-inactiveMar 14, 2017 · NHTSA campaign 17V177000 · 51 vehicles

Model years: 2012, 2013, 2014, 2015, 2016

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 AMG GT-S, GLC300, CLA250 and GLE300d 4Matic vehicles, 2013 C250, E350 BlueTec and G63 AMG vehicles, 2008-2014 C300 vehicles, 2013-2014 C300 4Matic and ML350 4Matic vehicles, 2009 C350 vehicles, 2014 CLS550, E350 4Matic, E350 Coupe 4Matic, E350 Wagon 4Matic, GLK350 and SL550 vehicles, 2012 CLS550 4Matic vehicles, 2012-2016 E350 vehicles, 2016-2017 GL450 4Matic vehicles, 2012-2014 ML350 4Matic BlueTec vehicles, 2015 S550, S550 4Matic and C300 4Matic Sedan vehicles, 2015-2016 C300 Sedan vehicles, and 2017 SL63 AMG vehicles. Various control units on these vehicles may have been updated with incorrect software, potentially affecting the correct deployment of the air bags in the event of a crash.

Risk: If the air bags do not deploy as intended in the event of a crash, there would be an increased risk of injury in the event of a crash.

Fix: MBUSA will notify owners, and dealers will update software in the affected control units, free of charge. The recall began April 21, 2017. Owners may contact MBUSA customer service at 1-800-367-6372.

What owners report

Short excerpts of recent complaints, with personal details removed. Full reports are on NHTSA.gov.

The contact owns a 2006 Mercedes-Benz E-350. The contact stated that the sensotronic brake control warning was illuminated. The contact researched and found information about warranty coverage for 2006-2010 models with a 25-year warranty. The vehicle was taken to the dealer, who diagnosed that the…

Received Sep 23, 2026 · NHTSA complaint 11766341

The vehicle was parked when the steering wheel locked , and the headrest. The electrical for my headlight driver side low beam gave me a warning lamp message.

Received Sep 16, 2026 · NHTSA complaint 11764591

An Intoxalock ignition interlock device was installed in my 2023 Mercedes-Benz E-Class on May 7, 2026. Following installation, the vehicle experienced repeated electrical/no-start problems and incidents in which it became immobilized and could not be moved, requiring towing. On one occasion the…

Received Aug 18, 2026 · NHTSA complaint 11757591

While driving my 2026 Mercedes-Benz E350 (rear-wheel drive) at approximately 40 mph, I began slowing for a traffic light. As I approached the intersection, the vehicle suddenly experienced what appeared to be a catastrophic electronic failure. Without warning, the vehicle became almost completely…

Received Jul 30, 2026 · NHTSA complaint 11753822

The digital instrument cluster and center infotainment display screen went completely black and blank while the vehicle was in motion. This immediate failure blinded the driver to critical safety telemetry, including the current vehicle speed, gear positioning, and active safety warning telltales…

Received Jun 23, 2026 · NHTSA complaint 11746077

Frequently asked questions

Do all Mercedes-Benz E350s have electrical system problems?

No. NHTSA has 179 owner complaints about electrical system for the Mercedes-Benz E350. Complaint data shows that the problem is reported, not how many of all cars sold are affected.

Was there a recall on the Mercedes-Benz E350 electrical system?

Yes: 9 safety recalls list electrical system. Check your VIN on NHTSA.gov to see whether the fix was done on your car.

What do owners say about electrical system problems on the Mercedes-Benz E350?

The most frequent phrase is “wiring harness”, in 10 of 179 complaints.

Other Mercedes-Benz E350 problems

See all Mercedes-Benz E350 problems.