Mercedes-Benz E350 Power Train Problems

Source: NHTSA · Updated Oct 13, 2026 · 130 complaints analyzed

Owners have filed 130 complaints with NHTSA about power train problems on the Mercedes-Benz E350 across 16 model years. The 2006 model year has the most (37). The words owners use most often: “balance shaft” (7% of reports).

What owners describe

Phrases that appear unusually often in these complaints compared with complaints about other cars.

  • Balance shaft: mentioned in 9 of 130 complaints (7%)
  • Conductor plate: mentioned in 7 of 130 complaints (5%)

How much does it cost to fix?

Owners who wrote down what they paid or were quoted put the typical power train repair on the Mercedes-Benz E350 at $5,900, and half of them between $4,050 and $8,700.

Based on 13 NHTSA complaints about this problem alone that state a repair bill or quote (2011–2017), converted to 2026 dollars with the U.S. consumer price index. These are owners' own figures, not a quote: they include dealer quotes, and owners who file complaints often faced larger repairs, so they can run higher than typical shop prices. Prices vary by shop, region and warranty coverage. How we calculate this.

At what mileage do power train problems happen?

Based on 101 complaints that reported the odometer reading.

Under 10k miles14 · 14%
10k–25k miles3 · 3%
25k–50k miles20 · 20%
50k–75k miles20 · 20%
75k–100k miles18 · 18%
100k–150k miles21 · 21%
150k+ miles5 · 5%

How serious are the reports?

Of 130 complaints, 8 mention a crash, 1 a fire, 6 an injury.

Mercedes-Benz E350 power train complaints by model year

Peak: 2006, with 37 complaints
2003: 1200312006: 37372007: 212007212008: 552009: 2200922010: 14142011: 6201162012: 10102013: 7201372014: 15152015: 1201512016: 552020: 1202012021: 332022: 1202212026: 11

n = 130 complaints · Source: NHTSA

Model yearPower Train complaintsShare of that yearMedian miles
2026 E3501100%—
2022 E350111%—
2021 E350323%—
2020 E350113%47,726
2016 E350510%84,000
2015 E35013%24,125
2014 E350155%48,500
2013 E35074%44,550
2012 E350105%20,000
2011 E35063%62,000
2010 E350148%94,000
2009 E35023%157,382
2008 E35053%71,888
2007 E350216%69,872
2006 E350379%72,740
2003 E350114%9,559

When owners reported it

Peak: 2014, with 16 complaints
2005: 320052007: 12008: 220082009: 22010: 320102011: 62012: 820122013: 62014: 162014162015: 92016: 620162017: 112018: 620182019: 52020: 720202021: 102022: 920222023: 82024: 520242025: 42026: 32026

n = 130 complaints · Source: NHTSA

Related recalls (1)

Power train:axle assembly; suspension:rearDo not driveDec 18, 2024 · NHTSA campaign 24V941000 · 17 vehicles

Model years: 2025

Problem: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2025 E 350, E 350 4MATIC, E 450 4MATIC, and E450 4MATIC station wagon vehicles. The camber strut bracket may have been improperly welded onto the rear axle carrier, possibly resulting in separation of the bracket from the rear axle carrier.

Risk: Rear axle carrier failure can cause a sudden loss of vehicle handling and control, increasing the risk of a crash.

Fix: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will replace the rear axle carrier, free of charge. Owner notification letters were mailed January 22, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024120015.

What owners report

Short excerpts of recent complaints, with personal details removed. Full reports are on NHTSA.gov.

Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. [redacted], internal code 21P1590208) to replace out-of-spec ignition coils on 657 vehicles from model year 2021, including the E-Class. My VIN was not…

Received Aug 8, 2026 · NHTSA complaint 11755689

While driving my 2026 Mercedes-Benz E350 (rear-wheel drive) at approximately 40 mph, I began slowing for a traffic light. As I approached the intersection, the vehicle suddenly experienced what appeared to be a catastrophic electronic failure. Without warning, the vehicle became almost completely…

Received Jul 30, 2026 · NHTSA complaint 11753822

With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .

Received Jan 4, 2026 · NHTSA complaint 11708688

Major issue found with engine cylinder head in various models with 2.0 Liter Turbo charged engines (Engine code M260 or M264). Cylinder heads have premature wear at valve seats, causing engine misfires and unsafe driving conditions. (Sudden loss of power, even on freeways.) Mercedes-Benz had…

Received Oct 23, 2025 · NHTSA complaint 11695193

The contact owned a 2012 Mercedes-Benz E350. The contact stated that while attempting to shift to drive(D), the gear shifter detached from the steering column. No warning light was illuminated. Neither a dealer nor an independent mechanic was contacted. The vehicle was not taken to a dealer or…

Received Aug 25, 2025 · NHTSA complaint 11682880

Frequently asked questions

Do all Mercedes-Benz E350s have power train problems?

No. NHTSA has 130 owner complaints about power train for the Mercedes-Benz E350. Complaint data shows that the problem is reported, not how many of all cars sold are affected.

Was there a recall on the Mercedes-Benz E350 power train?

Yes: 1 safety recall list power train. Check your VIN on NHTSA.gov to see whether the fix was done on your car.

How much does it cost to fix power train problems on the Mercedes-Benz E350?

Owners report a typical cost of $5,900 (half paid between $4,050 and $8,700), from 13 complaints that state a repair bill or quote, in 2026 dollars.

What do owners say about power train problems on the Mercedes-Benz E350?

The most frequent phrase is “balance shaft”, in 9 of 130 complaints, followed by “conductor plate” (7).

Other Mercedes-Benz E350 problems

See all Mercedes-Benz E350 problems.